EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel
نویسندگان
چکیده
BACKGROUND Aim of this in-vitro-study was to assess the remineralization potential of a tooth cleaning tablet with different fluoride content. METHODS Twenty three caries free impacted third molars were examined, enamel surfaces were wax coated leaving two 3 x 4 mm windows for exposure to demineralization/remineralization cycles. The teeth were randomly assigned to 4 groups of 5 control and 6 experimental teeth. Demineralization by standardised HEC-gel, pH 4.7 at 37 degrees C for 72 h, was alternated by rinsing in remineralization solution, pH 7.0 at 37 degrees C for 72 h, total challenge time 432 h. The negative control group N was treated during remineralization cycles with saline; positive control group P was treated with remineralization solution; experimental group D1 was exposed to remineralization solution containing Denttabs-tablets with 1450 ppm F; experimental group D2 was exposed to remineralization solution and Denttabs-tablets with 4350 ppm F. Each tooth was cut into serial sections and analyzed by polarized light microscopy for assessment of the different zones of white-spot lesions in 3 representative sections. Statistical analysis was based on the Mann-Whitney-Test. RESULTS Both control groups N(-) and P(+) exhibited characteristic white-spot lesions. The remineralization and the demineralization inhibition of the lesions increased considerably from N<P < D1<D2. Denttabs-2 administration showed partial/total remineralization including lamination and/or disappearance of the body of the lesion. The different results of all 4 groups were statistically highly significant (p < 0.01) with both tests. CONCLUSION Based on these results the novel Denttabs formulation represents a highly effective oral hygiene product and the remineralization is correlated to the fluoride content.
منابع مشابه
In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel
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عنوان ژورنال:
- BMC Oral Health
دوره 9 شماره
صفحات -
تاریخ انتشار 2009